九游平台_九游（中国）

　　1.九游平台_九游（中国）经历：

　　2008-2012年 河北农业大学 生物技术????学士学位

　　2012-2017年 北京大学 细胞生物学???? 博士学位

　　2.工作经历：

　　2017年7月-2019年8月??中国科学院生物物理研究所，项目副研究员

　　2019年9月至今??九游平台_九游（中国），副研究员

　　综合运用多组学手段多层次解析衰老及相关疾病的发生发展机制，探究新型干预靶标。

（#共同第一作者）

1. Sun S^#, Li J^#, Wang S^#, Li J^#, Ren J^#, Bao Z^#, Sun L^#, Ma X^#, Zheng F, Ma S, Sun L, Wang M, Yu Y, Ma M, Wang Q, Chen Z, Ma H, Wang X, Wu Z, Zhang H, Yan K, Yang Y, Zhang Y, Zhang S, Lei J, Teng ZQ, Liu CM, Bai G, Wang YJ, Li J, Wang X, Zhao G, Jiang T, Belmonte JCI, Qu J, Zhang W, Liu GH. CHIT1-positive microglia drive motor neuron aging in the primate spinal cord. Nature. 624(7992):611-620.
2. Wang S^#, Zheng Y^#, Li J^#, Yu Y^#, Zhang W^#, Song M, Liu Z, Min Z, Hu H, Jing Y, He X, Sun L, Esteban C, Chan P, Qiao J, Zhou Q, Belmonte JC, Jing Qu, Tang F, Liu GH. Single-cell transcriptomic atlas of primate ovarian aging. Cell. 2020. 180(3): 585-600. (Cover story)
3. Zhang W^#, Li J^#, Suzuki K^#, Qu J^#, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging. Science. 2015. 348(6239):1160-1163.
4. Li J^#, Zheng Y^#, Yan P^#, Song M^#, Wang S^#, Sun L, Liu Z, Ma S, Chan P, Zhou Q, Belmonte JC, Zhang W, Liu GH, Tang F, Qu J. A single-cell transcriptomic atlas of primate pancreatic islet aging. National Science Review. 2021. 8(2):nwaa127.
5. Li J^#, Zhou X^#, Liu X^#, Ren J^#, Wang J, Wang W, Zheng Y, Shi X, Sun T, Li Z, Kang A, Tang F, Wen L, Fu W. Detection of colorectal cancer in circulating cell-free DNA by methylated CpG tandem amplification and sequencing. Clinical Chemistry. 2019. 65(7):916-926.
6. Yang J^#, Li J^#, Suzuki K^#, Liu X, Wu J, Zhang W, Ren R, Zhang W, Chan P, Belmonte JC, Qu J, Tang F, Liu GH. Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding. Cell Research. 2017. 27(9):1178-1181.
7. Wen L^#, Li J^#, Guo H^#, Liu X^#, Zheng S, Zhang D, Zhu W, Qu J, Guo L, Du D, Jin X, Zhang Y, Gao Y, Shen J, Ge H, Tang F, Huang Y, Peng J. Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients. Cell Research. 2015. 25(11):1250-1264.

综述：

1. Biomarkers of aging. Science China Life Science. 2023. 66(5):893-1066. (Cover story)
2. The landscape of aging. Science China Life Science. 2022. 65(12): 2354–2454.